A protein once thought to simply help cancer cells avoid death turns out to do much more. MCL1 actively drives cancer ...

The kinase mTOR (mammalian target of rapamycin) is part of an evolutionarily conserved pathway that couples cell growth and metabolism to inputs from the environment in all eukaryotes. mTOR exists in ...

The serine/threonine protein kinase mechanistic target of rapamycin (mTOR) is evolutionarily conserved and modulates protein synthesis, cell growth, and cellular autophagy in response to distinct ...

Cytotoxic T lymphocytes play a crucial role in adaptive immunity, primarily defending against tumors and viruses. These cells develop within the thymus gland and undergo rapid activation upon ...

Angelini Pharma has licensed a preclinical-stage mTOR inhibitor from South Korean biotech Sovargen with potential for genetic forms of epilepsy and other brain disorders. The $550 million-plus deal ...