San Francisco 49ers running back Christian McCaffrey reacted to the devastating injury suffered by George Kittle on Sunday.

Christian McCaffrey reacted to George Kittle's social media post following the star tight end's season-ending Achilles injury ...

Up next for the 49ers are the No. 1-seeded Seattle Seahawks, who defeated San Francisco in Week 18, 13-3, to earn the ...

Sunday's road win over the Eagles gave the 49ers plenty of reason to celebrate, but the locker room party was muted a bit due ...

Our 2026 fantasy football RB rankings reveal Bijan Robinson at No. 1, major breakout candidates, and why Christian McCaffrey ...

No problem for the San Francisco 49ers. Behind a valiant effort from Brock Purdy, Christian McCaffrey and an undermanned ...

San Francisco 49ers running back Christian McCaffrey breaks down his Wild Card Weekend trick play touchdown that came on a 29 ...

San Francisco 49ers react to celebratory news on Christian McCaffrey ahead of playoff matchup against the Philadelphia Eagles ...

The 49ers lost George Kittle but upset the defending Super Bowl champions with two fourth-quarter touchdowns in an NFC ...

The All-Pro running back and hero of the Wild Card win over the Eagles shares a special moment with his wife after the game.

Watch the best plays from San Francisco 49ers running back Christian McCaffery's 114-yard game against the Philadelphia ...

PHILADELPHIA — Brock Purdy threw a go-ahead 4-yard touchdown pass to Christian McCaffrey late in the fourth quarter, San ...