From her early film debut to becoming one of Bollywood’s highest-paid actresses, her journey includes blockbuster films, ...
Researchers have identified the specific structural loops in G-quadruplex DNA that allow it to act as a chaperone, preventing ...
The firm is betting that adding the G-quadruplex stabilizer to the ADC will improve outcomes in HER2-low breast cancer patients.
Condo sales at the Downtown Brooklyn supertall — the first of its kind outside Manhattan — relaunched this June, a year after ...
CX-5461 is the first G-quadruplex (G4) stabilizer in development. It has shown promising activity in early-phase trials for breast cancer and other solid tumors in study sponsored by SU2C-CCTG in ...
The combination with Enhertu aims to improve treatment outcomes for HER2-low patients and expand therapeutic options.
Department of Chemistry, Graduate School of Science, Kyoto University, Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto 606-8502, Japan, NEC Soft, Ltd., VALWAY Technology ...
The global ADC market is projected to grow at a CAGR of 28.4%, reaching approximately USD 47 billion by 2029. Analysts believe that Senhwa's clinical development strategy combining CX-5461 and ...
Artificial intelligence has just redrawn the map of our genome’s control room, revealing hundreds of thousands of tiny DNA ...
AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.
An international team, including researchers from HSE University, has created the first comprehensive map of quadruplexes—unstable DNA structures ...
An international team, including researchers from HSE University, has created the first comprehensive map of ...