Neurodegenerative conditions such as Parkinson’s disease and Alzheimer’s disease involve progressive neuronal loss due to disease-induced damage. An enzyme known as dual leucine-zipper kinase (DLK) ...
Blue mold, caused by Penicillium expansum, is one of the most destructive postharvest diseases, leading to economic losses across fruit supply chains. Beyond rot, the fungus contaminates fruit-based ...
Mesenchymal stem cells have the potential to differentiate into various cell lineages, including adipocytes and osteoblasts. The induction of adipocyte differentiation by glucocorticoids (GCs) not ...
One of the most revolutionary upgrades to ever happen to the fashion industry was the introduction of the zipper. If you prefer zip-up clothes to button-downs, you're not alone. Zippers make getting ...
ABSTRACT: Despite aggressive treatment and recent advances, cancers of the colon and rectum remain a leading cause of death worldwide. In the case of rectal cancer, chemo-radiotherapy (CRT) is given ...
Leucine is an amino acid important for your muscle health and blood sugar levels. Many foods contain it, including eggs, seeds, oats, and legumes. You may have heard about an essential amino acid ...
Intraflagellar transport (IFT) is an evolutionarily conserved mechanism essential for the assembly and maintenance of most eukaryotic cilia and flagella, including mammalian sperm tails. Depletion of ...
Researchers have identified a family of enzymes whose inhibition both protects neurons and encourages their growth, a pathway to potential new treatments for neurodegenerative diseases from ...
Esophageal squamous cell carcinoma (ESCC) is a common gastrointestinal malignancy and is one of the most important cause of cancer related mortalities in the world. However, there is no clinically ...
A high grain yield is undoubtedly a desirable trait in cereal crops. Floret fertility is a key factor which determines the number of grains per inflorescence of cereals such as bread wheat or barley.
Glucocorticoids (GCs) are steroid hormones secreted as the end-product of the neuroendocrine stress cascade. Both absence and elevated GC mediate neurotoxic responses, suggesting that a narrow window ...
Neuropathic pain resulting from nerve injury can become persistent and difficult to treat but the molecular signaling responsible for its development remains poorly described. Here, we identify the ...
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