A pancreatic elastase test measures how much elastase is in your stool. Low levels of fecal elastase may mean your pancreas isn't working properly. The most common symptom of this condition is having ...
Daily dosing may reduce the metabolic drop-off that occurs prior to each weekly augmentation; therefore, alvelestat represents a potential oral disease-modifying treatment for AATD. Alvelestat ...
Elastase is a powerful enzyme that plays a critical role in various biological processes, both in physiological and pathological contexts. It belongs to the family of serine proteases, which are ...
Pancreatic elastase is the digestive enzyme the pancreas produces to help digest food. Doctors can measure elastase levels by testing a stool sample. Low levels could indicate exocrine pancreatic ...
Exocrine pancreatic insufficiency (EPI) causes clay-colored, greasy stools that smell foul. A stool test to check for low levels of the elastase enzyme can help diagnose the condition. The pancreas ...
COPD isn’t usually hereditary; it’s caused by exposure to pollutants like cigarette smoke. But some people do inherit a protein deficiency that increases their risk of COPD. A hacking cough and ...
11 C-NES was obtained with a radiochemical purity higher than 98% and a molar activity in the range of 180–330 GBq/μmol. Chemical purity was high, with no traces of the precursor GW611437. The very ...
Severe congenital neutropenia (SCN) is a rare hematological condition with heterogenous genetic background. Neutrophil elastase (NE) encoded by ELANE gene is mutated in over half of the SCN cases. The ...