1don MSN
New method reveals how mutations drive transthyretin amyloidosis and guides precision drug design
An international research team reveals new molecular mechanisms associated with pathogenic mutations in the protein ...
The Chosun Ilbo on MSN
Global and Korean Pharma Race Alzheimer's Drug Development
U.S. pharmaceutical company Eli Lilly plans to disclose the top-line results of its phase 3 clinical trial for ‘remternutux,’ a new drug candidate being developed as a successor to its Alzheimer’s ...
An international research team reveals new molecular mechanisms associated with pathogenic mutations in the protein transthyretin that cause ...
TAG24 NEWS on MSN
Microplastics weaken biological barrier that protects brain
“Microplastics actually weaken the blood-brain barrier, making it leaky. “Once that happens, immune cells and inflammatory ...
Calcium alpha-ketoglutarate, a naturally occurring metabolite, can restore key memory-related brain functions that have been disrupted in Alzheimer’s disease.
Singapore has one of the highest life expectancies in the world, yet many individuals spend almost a decade in poor health toward the end of life. Scientists from the Yong Loo Lin School of Medicine, ...
Alzheimer's disease (AD) is a serious neurodegenerative disease largely affecting older adults. Apart from age, it also shows ...
3don MSN
Common blood protein protects patients from lethal 'black fungus' infection, new study finds
Albumin is the most common protein in the blood, a vital molecule produced by the liver that helps maintain fluid balance and ...
4don MSN
Boosting the cell's own cleanup: New class of small molecules accelerate natural protein degradation
Proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in ...
Protein aggregation exhibits a dual role in biology, especially in neural systems. While pathogenic aggregates of proteins such as Aβ, tau, and α-synuclein ...
Acumen Pharmaceuticals is developing ACU193 as the first clinical-stage therapeutic to selectively target toxic soluble amyloid-β oligomers (AβOs), which are an early and persistent driver of ...
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