An investigator reported the results of a prespecified interim analysis of the phase 3 I CAN trial of ravulizumab for immunoglobulin A nephropathy.

Participants in the treatment group experienced a 93.5% reduction in urine soluble C5b9 levels from baseline to 24 months.

Telitacicept was associated with 6 times the odds of a decrease in proteinuria compared with immunosuppressive treatment at 48 weeks.

Living kidney donation is associated with a modestly increased risk of gestational hypertension, preeclampsia, or eclampsia. Women who become pregnant after donating a kidney face increased risks of ...

The randomized VIDEO-KD trial tested the value of an ESKD video decision aid vs usual care for advanced care planning among older patients with advanced CKD.

Sparsentan lowered blood pressure more than irbesartan at week 8, with mean differences of -7.2 mmHg systolic and -5.6 mmHg diastolic.

Bodily pain, vitality, and general health perceptions showed stronger associations with quality of life at lower proteinuria thresholds.

Clinically approved drugs induced ChAT expression and acetylcholine production in podocytes in vivo, suggesting the pathway could be pharmacologically targeted.

Across all patients, higher urinary CD93 was strongly associated with a faster time to a 40% decline in eGFR and a faster time to kidney failure.

Praliciguat alone or with enalapril as background therapy in a mouse model of primary FSGS and a rat model of secondary FSGS showed that praliciguat alone offered no benefit.

An observational study found that living in neighborhoods with high urban heat intensity reduces the chances of textbook surgical recovery.

Surveillance strategies following surgery for non-clear cell renal cell carcinoma (nccRCC) may need to differ from clear cell RCC.