BACKGROUND: Fontan circulatory failure (FCF) is a chronic state in palliated single ventricle heart disease with high morbidity and mortality rates, including heart failure, multisystem end-organ ...

BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

BACKGROUND: Evaluation of whether dyspnea has a cardiac cause is essential. Guidelines from 2016 were reported to result in a ...

European Stroke Organisation Conference May 21–23, 2025 Session: Intravenous Thrombolysis in Acute Ischemic Stroke: Expanding Indications and Evidence Gaspard Gerschenfeld from Paris, France, ...

Cardiovascular-kidney-metabolic (CKM) syndrome is a novel construct recently defined by the American Heart Association in response to the high prevalence of metabolic and kidney disease.

ORION-13 (Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia) is the first study to evaluate the efficacy, safety, and tolerability of ...

Cardiac intensive care units are witnessing a demographic shift, characterized by patients with increasingly complex or end-stage cardiovascular disease with a greater burden of concomitant comorbid ...

Blockade of IL1RAP (interleukin 1 receptor associated protein) was recently shown to reduce atherosclerosis in mice, but the effect on human vascular cells is largely unknown. Targeting the IL1RAP ...

Writing committees are instructed to follow the methodology for performance development 1, 2 and to ensure that the measures developed are aligned with ACC/AHA clinical practice guidelines. The ...

Poor sleep health is associated with cardiometabolic disease and related risk factors, including heart disease, stroke, elevated blood pressure and lipid levels, inflammation, glucose intolerance, ...

The science of cardiac rehabilitation and the secondary prevention of cardiovascular disease has progressed substantially since the most recent American Heart Association and American Association of ...

Historically, investments in specialized pediatric care, such as congenital cardiac care, have been deprioritized in LMIC due to the greater burden of “high prevalence” conditions such as malnutrition ...