Background Antimicrobial resistance (AMR) is a growing global health crisis and is particularly relevant to people living ...

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Recommendations Long-term macrolide treatment could be offered to reduce exacerbations in those with high exacerbation rates (ie, 3 or more per year). (Strong) The dosing regimens with the greatest ...

Background Smoking has been considered an important risk factor for idiopathic pulmonary fibrosis (IPF) incidence. However, there are no population-based large-scale studies demonstrating the effects ...

This document is the result of a joint initiative by the British Thoracic Society (BTS) and the Society of Cardiothoracic Surgeons of Great Britain and Ireland (SCTS) to produce detailed ...

Rationale Estimating the causal effect of an intervention at individual level, also called individual treatment effect (ITE), may help in identifying response prior to the intervention. Objectives We ...

COPD is a progressive disease where airway inflammation plays an important part. Previously, there were large expectations that regular anti-inflammatory treatment with inhaled corticosteroids (ICS) ...

Methods Pre-clinical work captured clinically relevant extremes of respiratory parameters using a pediatric mannequin and mechanical ventilation. Biosensor data was compared to ventilator-measured ...

The 2020 coronavirus pandemic has been particularly difficult for people living with chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD). COPD is associated with ...

Background Up to 50% of patients suffering acute pulmonary embolism (PE) demonstrate impaired pulmonary vascular recovery at follow up despite optimal anticoagulation, impacting negatively on ...

Background Coding practices impact the recorded prevalence of disease. Sepsis, most commonly caused by pneumonia, remains a common cause of mortality worldwide. In April 2017, NHS Digital issued new ...

Background and objectives IgG4-related disease (IgG4-RD) is a multi-system fibro-inflammatory disorder originally described in association with autoimmune pancreatitis (AIP), usually but not always in ...