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2025 Week 1 NFL score predictions, odds, picks today: Proven expert unveils precise scores for each NFL game SportsLine expert Eric Cohen reveals his score predictions for the 16 games in Week 1 ...
All of the updated Week 1 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and NFL predictions you need to make the best Week 1 NFL picks now.
Here are the spreads for all 16 games of Week 1 of the 2025 NFL season.
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