Robinow syndrome is a rare skeletal dysplasia marked by mesomelic limb shortening, characteristic craniofacial features and genital hypoplasia. It arises from mutations in components of Wnt signalling ...
Planar cell polarity core proteins Frizzled (Fz)/Dishevelled (Dvl) and Van Gogh-like (Vangl)/Prickle (Pk) are localized on opposite sides of the cell and engage in reciprocal repression to modulate ...
Convergent extension (CE) is a fundamental morphogenetic process where oriented cell behaviors lead to polarized extension of diverse tissues. In vertebrates, regulation of CE requires both ...
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