International collaboration produces detailed models of the 3D genome over time in cells

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...
Max Planck Society

PhD student or Postdoctoral researcher (f/m/d) | Structure and Dynamics of Chromosomes

The Max Planck Institute of Biophysics is an internationally leading research institution in the fields of structural biology, biophysics and cell biology located at the center of the Frankfurt ...
GitHub

NeRV-3D-DC: A Nonlinear Dimensionality Reduction visualization method for 3D Chromosome Structure Reconstruction with high Resolution Hi-C Data

../GM12878:results of 50kb and 5kb resolution in real Hi-C data ../IMR90:results of 50kb and 5kb resolution in real Hi-C data ...
IEEE

KaryoNet: Chromosome Recognition With End-to-End Combinatorial Optimization Network

Abstract: Chromosome recognition is a critical way to diagnose various hematological malignancies and genetic diseases, which is however a repetitive and time-consuming process in karyotyping. To ...
Nature

Systematic maps reveal how human chromosomes are organized

When you think of a chromosome, you might imagine an X-shaped structure. But chromosomes take this shape only during cell division; the rest of the time, they adopt a structure that looks amorphous ...