The nonsteroidal mineralocorticoid receptor antagonist finerenone has been reported to improve kidney and cardiovascular outcomes in persons with type 2 diabetes and chronic kidney disease (CKD).

Recent FDA actions related to leucovorin have caused confusion. There is still a lack of scientific evidence establishing that the drug is a safe and effective treatment for autism.

Explore this issue of The New England Journal of Medicine (Vol. 392 No. 5).

As a legacy of African enslavement, structural racism affects both population and individual health in three interrelated domains: redlining and racialized residential segregation, mass incarceration ...

The CMS Innovation Center is approaching the next negotiation cycle for the CGT Access Model. Several considerations will guide the selection of future candidate diseases and potential new model ...

New AI-based software for generating patient notes purposely filters out social “chitchat,” but a primary care physician sees serious risks in that practice, for doctors and patients alike.

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 23).

A 26-year-old man with chronic kidney disease presented with white, sharply demarcated, adherent plaques on the tongue. The blood urea nitrogen level was more than 225 mg per deciliter. The appearance ...

Explore this issue of The New England Journal of Medicine (Vol. 393 No. 18).

Base editors can correct disease-causing genetic variants. After a neonate had received a diagnosis of severe carbamoyl-phosphate synthetase 1 deficiency, a disease with an estimated 50% mortality in ...

Explore this issue of The New England Journal of Medicine (Vol. 392 No. 3).

Explore this issue of The New England Journal of Medicine (Vol. 392 No. 16).