A protein once thought to simply help cancer cells avoid death turns out to do much more. MCL1 actively drives cancer ...

Loss of PTEN function leads to activation of phosphoinositide 3-kinase (PI3K) signaling and Akt. Clinical trials are now testing whether mammalian target of rapamycin (mTOR) inhibition is useful in ...

Cytotoxic T lymphocytes play a crucial role in adaptive immunity, primarily defending against tumors and viruses. These cells develop within the thymus gland and undergo rapid activation upon ...

Angelini Pharma has licensed a preclinical-stage mTOR inhibitor from South Korean biotech Sovargen with potential for genetic forms of epilepsy and other brain disorders. The $550 million-plus deal ...

A new study reveals how a single cancer protein may simultaneously drive tumor survival and metabolic control, uncovering a ...

Variation in health-related quality of life (HRQOL) by line of therapy, age, and gender among patients with chronic lymphocytic leukemia. Predictive factors associated with achievement of major ...

Cummins Inc. CMI recently announced that it will acquire Meritor, Inc. MTOR to reinforce its electric and hybrid vehicle parts offerings. The deal comes at a time when the demand for climate-friendly ...