This Brush Up is sponsored by MilliporeSigma. Learn more about therapeutic synthesis pathways. Drug development is a process that spans many years, from the initial phase of identifying potential drug ...

According to a new study published in Nature Communications, researchers at the Department of Laboratory Medicine, Karolinska Institutet, have made a significant leap in drug discovery and development ...

In high-tech labs, workers are generating data to train A.I. algorithms to design better medicine, faster. But the transformation is just getting underway. By Steve Lohr Photographs by Spencer Lowell ...

Ibogaine’s unconventional “matrix pharmacology” may underlie both its therapeutic promise and unpredictable cardiac risks.

Safety is a major cause of attrition in drug discovery and development 1,2 and is, thus, a key consideration when making decisions at the major transition points in the drug pipeline (Box 1).

Medicinal chemistry, also known as pharmaceutical chemistry, is a branch of chemistry focused on the development of new drugs and the improvement of existing ones. It is an interdisciplinary field ...

Glucagon-like peptide agonists (GLP-1s, like Ozempic, Wegovy, and Mounjaro) have been hailed as breakthroughs. From statins to Viagra, occasionally a drug development breakthrough occurs that is ...

Sandra Gostynska and Augen Pioszak, Ph.D., of the University of Oklahoma are authors of a new paper in Science Signaling that sheds light on the hormone amylin and the receptors it targets in the ...

When pharmaceutical companies develop a novel drug for the market, several steps are required to assess and regulate its safety, effectiveness, manufacturability, and reliability. These processes, and ...