A joint research group team led by Sayuri Tsukahara and Tetsuji Kakutani of the University of Tokyo has clarified a mechanism of how retrotransposons, genetic elements that can "jump around" ...

A research team has clarified a mechanism of how retrotransposons, genetic elements that can 'jump around' chromosomes and are known drivers of evolution, preferentially insert in the centromere. A ...

Retrotransposons are mobile genetic elements that replicate through an RNA intermediate and integrate into host genomes via specialised mechanisms. Among these, non-long terminal repeat (non-LTR) ...

Retrotransposons are evolutionarily ancient genes that “jump” around the human genome leaving a slew of repeat nucleotide sequences in their wake. These repeats can disturb normal gene function.

A new editorial was published in Oncoscience (Volume 11) on July 13, 2024, entitled, "Unveiling retrotransposon-derived DNA zip code for myeloma cell internalization." The complex interplay between ...

Figure 2. Diagrammatic representation of kodikaz therapeutic solutions’ zip-code technology application to various human diseases. The complex interplay between extracellular genetic material and the ...

The process of cellular differentiation, in which human pluripotent stem cells (hPCSs) progress from primitive to developmentally advanced states, is a fundamental aspect of life. Understanding this ...

Our genomes are peppered with DNA segments called retrotransposons that can move from place to place. When unleashed, some can kill nerves and promote inflammation — a discovery that may inspire ...