Topochemical polymer synthesis and reactions exploit the unique spatial arrangement of reactant molecules in the solid state to achieve controlled polymer formation. By pre‐organising monomers within ...

Mechanochemical synthesis harnesses mechanical energy to drive chemical transformations under solvent‐minimised or solvent-free conditions. This approach, frequently executed by ball milling or liquid ...

Recent technological advances have opened new possibilities for the efficient and sustainable synthesis of various valuable chemicals. Some of these advances rely on nanotechnologies, systems or ...

I am writing to express my displeasure regarding the letter to the editor by Julian Tyson (C&EN, March 14/21, 2022, page 5) about “metal-free” reactions (Feb. 14, 2022, page 20). Specifically, my ...

Highly reactive organometallic reagents, like organolithiums (molecules with a carbon–lithium bond) are essential reagents in organic synthesis because of their applications from polymer synthesis to ...

With artificial intelligence, scientists can design increasingly complex small molecule structures. Automation is critical for transforming these compounds from designs on a screen into actual ...