Stem cells are the original cell type from which all other cells and tissues in the body develop through a very tightly regulated process. However, how stem cells differentiate in addition to ...

Osteogenic differentiation describes the multistep process by which undifferentiated stem or progenitor cells adopt the phenotype and function of osteoblasts, the specialised cells responsible for ...

All cells in the body arise from a single fertilized egg. From this single origin, various specialized cells with widely differing tasks evolve through a process called cellular differentiation.

The Carta algorithm infers a differentiation map — including progenitor cell types and transitions between progenitor and terminal cell types — from high-throughput lineage tracing data. Applying ...

A unique and reliable approach for inducing NK cells from iPSCs (iNK) in a completely feeder-free environment was designed in this study. After 35 days, the cell proportion of CD3-CD56 + iNK Cells ...

A transient 4CL treatment during reprogramming yields human iPSCs with enhanced mesodermal, endodermal, and pancreatic ...

Manish Ayushman, a PhD student in bioengineering, has watched more than a thousand hours of microscopic footage of stem cells in the lab. At first, the cells seemed like they weren't doing much of ...

Engelman D, Hochstetter J, Bauduin A, et al. (Blanpain C, Simons BD Laboratory). "Sexual dimorphism in epidermal stem cell ...

The Regenerative Medicine Project at our institute is advancing therapeutic strategies for various diseases by introducing a range of modifications to human induced pluripotent stem (iPS) cells.

A study in BMC Medical Genomics finds that miR-183-5p is upregulated in the serum of adolescent idiopathic scoliosis patients ...