Industry is adapting to the increasing complexity and poor solubility and bioavailability of molecules in the pipeline. Poor solubility and low bioavailability have hindered the development pipeline ...

Solubility functions by a group of rules that determine how dissolvable a substance (solute) is in solvent and depends entirely on the physical and chemical properties of the solute and solvent. That ...

A large share of medicines developed today may never reach patients for a surprisingly simple reason: they cannot dissolve well enough in water. For most treatments, the oral route remains the gold ...

High-concentration injectable formulations present unique challenges. Poor solubility issues are often associated with small-molecule APIs formulated for oral administration. Solubility is also ...

SYNTECA BIO, an artificial intelligence (AI)-based drug development company, has secured a biobetter candidate with improved solubility over conventio ...

Solubility rules are your shortcut to knowing whether mixing two solutions will produce a solid precipitate or stay clear. By learning the key 'always soluble' ions and the common exceptions, you can ...

Enzymatic sulfation helps solve lignin’s solubility problem Adding sulfate groups to phenols improves the recalcitrant material’s solubility in water and should aid production of aromatic compounds ...

Introduction Have you ever added a spoon of sugar to your tea and wondered why it disappeared? Where did it go? The sugar did not actually disappear—it changed from its solid form into a dissolved ...