Medical Xpress

Integrative exome sequencing and machine learning identify new genes contributing to systemic sclerosis risk

Systemic sclerosis (SSc) is a severe autoimmune disease with complex genetic causes. Some genetic contributors have been identified, but others remain unknown, which has impeded development of ...
JD Supra

Is Your DNA Safe? DNA Sequencing Machines Found to Contain Critical Vulnerabilities

Illumina DNA sequencing machines are vulnerable to exploitation. Both the Cybersecurity and Infrastructure Security Agency (CISA) and the Food and Drug Administration (FDA) have published advisories ...
Medical Xpress

Machine learning algorithm brings long-read sequencing to the clinic

Long-read sequencing technologies analyze long, continuous stretches of DNA. These methods have the potential to improve researchers' ability to detect complex genetic alterations in cancer genomes.
Nanowerk

Nanopore DNA Sequencing: A Powerful Tool for Genetic Analysis

What is Nanopore DNA Sequencing? Nanopore DNA sequencing is a cutting-edge technology that enables the direct, real-time analysis of long DNA or RNA fragments. Unlike conventional sequencing methods ...
Wired

AI Is Building Highly Effective Antibodies That Humans Can’t Even Imagine

At an old biscuit factory in South London, giant mixers and industrial ovens have been replaced by robotic arms, incubators, and DNA sequencing machines. James Field and his company LabGenius aren’t ...
Nature

The evolution of DNA sequencing with microfluidics

In the 1990s, the Human Genome Project (HGP), which aimed to map the entire ~3 billion base pairs of the human genome, clearly demonstrated the technical challenges underlying the measurement of many ...
Forbes

Why Genome Sequencing Is So Controversial: 100,000 Newborns This Year Will Be Tested In The U.K., Joining NYC

A U.K. program—similar to one launched in New York last fall— will begin genome sequencing on 100,000 babies this year to figure out whether screening newborns for a wide range of conditions is ...
The Daily Illini

UI DNA sequencing stays updated on developing tech

Although it is an important technology for studying genomes, DNA sequencing was initially accomplished in 1977 by Frederick Sanger. Since its conception, the technology has developed rapidly. Alvaro G ...
Nature

Sequence-to-sequence translation from mass spectra to peptides with a transformer model

A fundamental challenge in mass spectrometry-based proteomics is the identification of the peptide that generated each acquired tandem mass spectrum. Approaches that leverage known peptide sequence ...
ascopubs.org

Whole exome sequencing and machine learning germline analysis of individuals presenting with phenotypes of extreme high and low risk of developing tobacco-induced lung ...

Integrating polygenic risk scores into clinical breast cancer models: Influence on prediction in diverse cohorts.
Science Daily

Machine learning algorithm brings long-read sequencing to the clinic

SAVANA uses a machine learning algorithm to identify cancer-specific structural variations and copy number aberrations in long-read DNA sequencing data. The complex structure of cancer genomes means ...