Explore technical features and comparative strengths of MaxQuant, Proteome Discoverer, FragPipe, and DIA-NN workflows.

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 possible variants-more combinations than atoms in the observable universe.

Protein sequencing presents different challenges than nucleic acid sequencing, meaning that proteomics has yet to benefit as much as genomics from the next-generation sequencing revolution. However, ...

Researchers headed by a team at the Centre for Genomic Regulation, Barcelona Institute of Science and Technology and at the Wellcome Sanger Institute have developed an AI tool that they say has made a ...

Enhancing protein identification accuracy is vital for proteomics; this article explores key technologies and statistical methods involved.

Protein design is crucial for the treatment of human diseases, but traditional protein design methods have some limitations. Site-directed mutagenesis is highly dependent on the physiological ...

New research headed by scientists at the Centre for Genomic Regulation (CRG) has demonstrated how the three-dimensional shape of a protein can be used to resolve deep, ancient evolutionary ...

Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...

This study is a valuable contribution that comprehensively identifies and characterizes LC3B-binding peptides through a bacterial cell-surface display screen covering approximately 500,000 human ...

MIT researchers have built an AI language model that learns the internal coding patterns of a yeast species widely used to manufacture protein-based drugs, then rewrites gene sequences to push protein ...