Boston, MA - Patients who receive high doses of the antidepressants citalopram or escitalopram could potentially develop QT-interval prolongation, a marker of a slight increased risk for ventricular ...

QT prolongation occurs when the heart muscle takes longer to contract and relax than usual. It can affect heart rhythms and lead to sudden cardiac arrest. The heart is a muscle that contracts and ...

For many years, moderate alcohol intake and its effect on health have been subject to much debate, particularly concerning cardiovascular health. Indeed, light-to-moderate use of alcohol has been ...

Purpose: The association of antipsychotic and antidepressant drugs with Q-T interval prolongation is reviewed. Summary: Prolongation of the Q-T interval can be of particular concern to practitioners ...

Studies comparing MMT to buprenorphine maintenance treatment (BMT) over 5-years found buprenorphine to be a safer drug for opioid maintenance treatment as it had no significant effect on QT ...

QT Prolongation Risk Assessed for Non-SSRI Antidepressants Although the FDA requires drug companies to do extensive side-effect testing on their products prior to approval, including QT and QTc ...

CredibleMeds, a valuable resource for prescribing physicians, now includes information from FDA drug labels to inform prescribers of any ECG monitoring recommendations, warnings for use in congenital ...

Arsenic trioxide (ATO) is a highly effective agent for the treatment of acute promyelocytic leukemia (APL). QT interval prolongation is common with ATO and can pose a barrier to effective ...

Evaluation of utility of pharmacokinetic studies in phase I combination trials. ApoStream, a novel device for antibody-independent capture of circulating cancercells (CCCs) from blood of patients with ...