The goal of this problem formulation was to identify scenarios where further risk analysis may be necessary. The conclusion of this problem formulation is that EPA will assess risks to consumers, the ...

NRC (2013) recommended that EPA address whether high dose exposures influence the shape of the dose-response curve. This could be addressed by performing sensitivity analyses in which the high level ...

This problem formulation and initial assessment examined likely 1,4-Dioxane exposure and hazard scenarios to workers and consumers based on current production, use, and fate information. The goal of ...

The risk-assessment paradigm that dates to the 1983 report Risk Assessment in the Federal Government: Managing the Process (NRC 1983) and has long been used by EPA has four components: hazard ...