Heart failure induces profound alterations in the absorption, distribution, metabolism and excretion of cardiovascular agents. Reduced cardiac output and splanchnic perfusion may delay ...
Izicopan achieved rapid and sustained inhibition of C5a/C5aR1 signalingPharmacokinetic results demonstrated dose-dependent exposure, with ...
Severe visual illnesses are increasing in our society, and effective treatments are missing for diseases as age-related macular degeneration, diabetic retinopathy, and glaucoma. Both industry and ...
A controlled rat study found that simulated 6,000-meter hypoxia raised dapagliflozin exposure 6.58-fold after acute exposure ...
A new review links rapid relapse after stopping JAK inhibitors in inflammatory skin diseases to primed hyperphosphorylated ...
Leverage predictive PK/PD models to identify risks early, reduce drug attrition, optimize development, and uncover revenue opportunities through regional and segment insights.Dublin, Oct. (GLOBE ...
A phase 1 study in patients with advanced non-small cell lung cancer treated with stereotactic radiotherapy to the primary tumor combined with durvalumab and tremelimumab. This is an ASCO Meeting ...
Frequency of comedication of proton pump inhibitors with crystalline dasatinib in chronic myeloid leukemia and effects on TKI-bioavailability. This is an ASCO Meeting Abstract from the 2024 ASCO ...
Appropriate selection of a drug regimen is crucial to the efficacy and safety of cardiovascular pharmacotherapy. In particular, when prescribing antithrombotic therapy, it is vital to avoid ...
Credit: Getty Images In a 3-part series, authors discussed the neurocognitive impact of long-term medications in patients with CKD. Patients with CKD may be more susceptible to cognitive adverse drug ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results