Despite considerable advances, and the abundance of organometallic reagents developed for additions to carbonyl compounds, three key challenges have endured. First, the dependence on stoichiometric, ...

Carbon–carbon bond formation is the basis for the biogenesis of nature's essential molecules. Consequently, it lies at the heart of the chemical sciences. Chiral catalysts have been developed for ...

Catalysis: They are essential in catalysis, particularly in processes like hydrogenation, hydroformylation, and polymerisation. For example, Ziegler-Natta catalysts, which are organometallic compounds ...

Organometallic reagents are essential tools in synthetic chemistry. They work even better and more effectively in combination with alkali alkoxides. The exact nature of this effect has never been well ...

Synthetic chemists prize organolithium reagents for their ability to build carbon-carbon bonds. But their extreme reactivity also makes them dangerous—they can spontaneously ignite when exposed to air ...

Organolithium and magnesium reagents are staples in chemical stockrooms. Useful in an array of reactions, they may experience their heaviest demand from cross-coupling reactions. In two such reactions ...