Genes hold the recipe for proteins, which are made of amino acids. DNA only has four letters, or nucleotides, and each sequence of three nucleotide bases, or codon, encodes for one amino acid. There ...

Researchers are adding new evidence to the emerging concept that 'silent' or synonymous mutations may have crucial consequences. Their study showed how a synonymous mutation in one gene can ...

Occasionally, single-letter misspellings in the genetic code, known as point mutations, occur. Point mutations that alter the resulting protein sequences are called nonsynonymous mutations, while ...

DNA has to be interpreted by cells. The letters or bases that make up genetic sequences are read in sets of three, and those three-base sequences are known as codons. Every codon encodes for one amino ...

A central assumption about so-called synonymous mutations, which are changes in the coding sequence of proteins that do not lead to changes in its amino acid sequence, is being questioned by a study ...

Barcelona, 23 July 2024 – Cancer is caused by genetic changes that occur in our cells over time. There are two main types of changes, namely somatic mutations, which are alterations in the DNA ...

Cystic fibrosis (CF) is an autosomal recessive disease due to a deleterious mutation in a chloride channel gene (CFTR = CF transmembrane conductance regulator), located on chromosome 7. From a ...

A team of scientists from Australia has recently identified a frameshift deletion mutation in ORF7a of the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The mutation ...

Congenital erythropoietic porphyria (CEP) or Günther’s disease is an inborn error of heme biosynthesis transmitted as an autosomal recessive trait and ...

Point mutations that alter the resulting protein sequences are called nonsynonymous mutations, while those that do not alter protein sequences are called silent or synonymous mutations. Between ...