A hidden “jack-in-the-box” mechanism inside T cells may hold the key to unlocking more powerful cancer immunotherapies.

T cell immunotherapies are on the cutting-edge of cancer treatments, but a full understanding of how they work has been ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...

Quantitative Drosophila pupal wing experiments support planar polarity depending on cell-scale signalling that does not involve depletion of a limited pool of core proteins or polarised transport on ...

Mitochondrial defects are associated with the development of diseases such as type 2 diabetes (T2D). Studies in mice and in human tissues, by researchers at the University of Michigan, have now found ...