Researchers at the Wellcome Sanger Institute used prime editing to develop a novel tool to predict the chances of successfully inserting a gene-edited sequence of DNA into the genome of a cell. An ...

Google's NotebookLM finally makes its auto-generated flashcards editable, letting learners fix and reword cards instead of regenerating them.

Prime editors (PEs) are promising genome-editing tools, but effective optimization of prime-editing guide RNA (pegRNA) design remains a challenge owing to the lack of accurate and broadly applicable ...

Computational methods have long had a pivotal role in advancing biophysics and structural biology 1,2. Genome-editing systems, such as CRISPR–Cas9 (ref. 3) and other CRISPR effector proteins 4, are ...