A mobile state of the kinesin–ADP head is discovered using multi- and single-molecule fluorescence polarization. The structure of the microtubule–kinesin complex has been determined by cryo-EM. The ...

Unlike a congested city commute, cellular traffic is efficient and highly regulated - thanks in part to a group of proteins known as motor molecules that use microtubules to haul vital cargo through ...

Kinesin is an ATP-driven molecular motor protein that moves processively along microtubules. Despite considerable research, the detailed mechanism of kinesin motion remains elusive. We applied an ...

For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo ...

A toddler running sometimes loses footing because both feet come off the ground at the same time. Kinesin motors that move materials around in cells have the same problem, which limits how fast they ...

Biophysicists at Stanford University have finally answered one of the most fundamental questions in molecular biology: How does the tiny motor molecule, known as kinesin, move across a living cell?

This is a preview. Log in through your library . Abstract Kinesin I can walk on a microtubule for distances as long as several micrometers. However, it is still unclear how this molecular motor can ...

Courtesy of Steven BlockIt had long been assumed that motor proteins would advance in discrete steps. However, the steps posed a challenge for measurement because they were small enough to be ...

The inside of a living cell has been compared to a train station at rush hour, with enzymes, chromosomes and other internal components constantly being shuttled along tiny fibrous tracks called ...