A new study reveals how partial subunit binding locks the brain's most common kainate receptor into a permanently open state.

In the mammalian CNS, the principle excitatory neurotransmitter is L-Glutamate, which acts through G-protein coupled (metabotropic) receptors and ligand gated ion channels (ionotropic receptors).

Neuroanatomical and pharmacological evidence implicates glutamate transmission in drug-environment conditioning that partly controls drug seeking and relapse. Glutamate receptors could be targets for ...

(−)Nicotine hydrogen tartrate (all doses calculated as free base) was purchased from Sigma (St Louis, MO). Operant chambers, circuit boards, interface modules, and SA software were from Coulbourn ...

In a bid to understand why mosquitoes may be more attracted to one human than another, Johns Hopkins Medicine researchers say they have mapped specialized receptors on the insects’ nerve cells that ...

Glutamate receptors are the primary mediators of excitatory transmission in the central nervous system and are mostly located on the dendrites of postsynaptic neuronal and glial cells, such as ...