A topical spray reduced pain by 34% in children undergoing intravenous procedures, such as injections and tube insertions (cannulation), compared with a placebo group. The findings from this ...

Taddio and colleagues performed a double-blind randomized controlled trial to evaluate the effectiveness of liposomal lidocaine 4% cream in reducing the pain, duration and failure rate of intravenous ...

In this report, the authors evaluated the utility of a topical cooling spray as a way to reduce pain during intravenous cannulation in an emergency department setting. The study group compared 103 ...