Premetastatic cancer cells often spread from the primary lesion through the lymphatic vasculature and, clinically, the presence or absence of lymph node metastases impacts treatment decisions. However ...

Immune cells continuously migrate into and out of tissues, blood and the lymphatic circulation (Box 1), where they provide immune surveillance and mediate immune responses. Tissue lymphatics and blood ...

The lymphatic system has long been considered mysterious. But the lymphatic system – and the lymph nodes within it – plays fascinating and important roles in health and disease, from fighting off ...

Cancer that starts in the lymph nodes is lymphoma. Cancer may also spread from other areas of the body to various lymph nodes, including the neck. Swollen lymph nodes are usually due to a cause other ...

The popliteal lymph nodes lie in the tissues behind a person’s knee. Infections and autoimmune conditions can cause them to swell. It is rare for cancer to affect the popliteal lymph nodes. According ...