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Best practice recommendations for clinical homologous recombination deficiency testing published

The Association for Molecular Pathology announced the publication of best practice recommendations for clinical laboratories developing and performing homologous recombination deficiency (HRD) testing ...
EurekAlert!

Association for Molecular Pathology publishes best practice recommendations for clinical HRD testing

ROCKVILLE, Md. – June 24, 2025 – The Association for Molecular Pathology, the premier global molecular diagnostic professional society, today announced the publication of best practice recommendations ...
EurekAlert!

Unraveling the molecular basis of Dmc1 filament assembly in homologous recombination

Homologous recombination (HR) is an important process that plays multiple crucial roles during meiosis, a type of cell cycle dedicated to sexual reproduction. During HR, homologous DNA molecules ...
ascopubs.org

Diagnosis of Ovarian Carcinoma Homologous Recombination DNA Repair Deficiency From Targeted Gene Capture Oncology Assays

Homologous recombination DNA repair deficiency (HRD) is a therapeutic biomarker for sensitivity to platinum and poly(ADP-ribose) polymerase inhibitor therapies in breast and ovarian cancers. Several ...
ascopubs.org

Homologous recombination deficiency score for predicting efficacy of platinum-based chemotherapy and PARPi maintenance therapy in ovarian cancer.

Overall survival in patients with BRCA-mutated platinum-sensitive relapsed ovarian cancer (PSROC) treated with olaparib maintenance: Real-world data of the C-PATROL study. Weekly BH009 in patients ...
ucdavis.edu

Cell Biologist Elected as a Fellow of the Royal Society

Professor Neil Hunter, Department of Microbiology and Molecular Genetics, has been elected as a Fellow of the Royal Society of the United Kingdom. Hunter, how is also an HHMI Investigator, studies the ...