Flux balance and network-based pathway analyses are theoretical tools aimed to find optimal steady state flux distributions in a metabolic network subject to additional constraints on the rates of the ...

A hybrid modeling framework to optimize Chinese hamster ovary cell cultures for monoclonal antibody (mAb) production reduces the number of modeling parameters needed while returning results that ...

This is a preview. Log in through your library . Abstract The accumulation of storage compounds is an important aspect of cereal seed metabolism. Due to the agronomical importance of the storage ...

In this study, a principle of cancer cell metabolism was elucidated by integrating 13 C-metabolic flux analysis with flux balance analysis. The findings reveal that glycolysis-dependent, less ...

Flux balance analysis of plant metabolism is an established method for predicting metabolic flux phenotypes and for exploring the way in which the plant metabolic network delivers specific outcomes in ...