Although you may never have heard of the cytochrome P450 superfamily of enzymes, these proteins play diverse and critical roles in humans through the metabolic processing of drugs, pesticides, fatty ...

The ensemble-function approach provides a quantitative catalytic model for serine proteases and identifies repeatedly evolved catalytic strategies. Credit: Science (2025). DOI: 10.1126/science.ado5068 ...

A team has used neutron crystallography to image all of the atoms in a radical intermediate of a copper amine oxidase enzyme. They disclosed previously unknown details, such as precise conformational ...

By reconstructing ancient nitrogen-processing enzymes, scientists are uncovering new clues about how early life survived on a ...

How can we know what life on Earth looked like more than three billion years ago, when rocks from that era are so rare and ...

Halogenated compounds are widespread in the pharmaceutical and agrochemical industries. But the reagents used to make them can produce hazardous waste and mixtures of compounds. Enzymes can provide a ...

The latest short science news items from C&EN. The team proposes that SAM plays a dual role in the reaction. It donates a methyl group to the enzyme’s cobalamin cofactor and then serves as a base when ...

Man prides himself upon his growing mastery over nature, but in the ultimate biochemical analysis nature remains the master of man. With their most sophisticated laboratory glassware and corrosive ...

NSF backs Nicole Buan’s three-year study mapping Methanosarcina acetivorans metabolism to understand methanogen biochemistry ...

Using a series of more than 1,000 X-ray snapshots of the shapeshifting of enzymes in action, researchers at Stanford University have illuminated one of the great mysteries of life – how enzymes are ...