During embryonic development, the entire nervous system, the skin and the sensory organs emerge from a single sheet of cells known as the ectoderm. While there have been extensive studies of how this ...

Bioscientists develop a method to observe patterns of early embryonic development, during which ectodermal cells diverge toward their fates as skin, organs and the nervous system. During embryonic ...

Embryonic patterning involves the complex interplay of multiple signalling pathways triggering gene regulatory networks, which, in turn, drive cell-fate choices and progenitor cell differentiation.

A cell aggregation of human pluripotent stem cells and amniotic ectoderm cells generated by the published culture method and mimicking the gastrulation event in human embryos. Gray: nuclei, Cyan: ...

Neural crest cells have been thought to originate in the ectoderm, the outermost of the three germ layers formed in the earliest stages of embryonic development. But their capacity to form derivatives ...

Bone morphogenetic protein (BMP) inhibits neural specification and induces epidermal differentiation during ectodermal patterning. However, the mechanism of this process is not well understood. Here ...

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilised egg, starts to develop, ...

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilized egg, starts to develop, ...

When the zygote, or the fertilised egg, starts to develop, the soon forming inner cell mass, a cluster of cells that will eventually develop into the individual, retains its pluripotent stem cell ...