MILAN — Tirzepatide (Mounjaro, Eli Lilly) improved markers of beta-cell function and insulin sensitivity in people with recent-onset type 2 diabetes (T2D), a new prespecified analysis of SURPASS-EARLY ...

Methods like this can help scientists sort through potential drug candidates faster and with more biological detail.

While humans can regularly replace certain cells, like those in our blood and gut, we cannot naturally regrow most other parts of the body. For example, when the tiny sensory hair cells in our inner ...

Using microscopic silicon nanowires, Singh and his team delivered the instructions into more than 90% of aging T cells without damaging them. The goal wasn't to reverse aging. It was to restore enough ...

Selecting specific cells to be used in an investigational therapy has led to improved recovery of heart function in a new study employing a lab model for myocardial infarction, the medical term for ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

Immunotherapies, especially CAR T-cell therapy, have fundamentally changed cancer treatment in recent years, particularly for ...

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME). Their anti-tumor functions include recognizing tumor-associated antigens, ...

Explore new St. Jude research finding how removing the immune response “brake” gene ZMYND8 led to better control of solid tumors and chronic viral infections.