Linda Truebestein, Harald Hornegger, Dorothea Anrather, Markus Hartl, Kaelin D. Fleming, Jordan T. B. Stariha, Els Pardon, Jan Steyaert, John E. Burke, Thomas A ...
PI3K signaling pathways. Upon activation by RTK, GPCR, Integrin, and Ras, p110 loses inhibition by p85 and converts PIP2 to PIP3. PIP3 recruits AKT to the cell membrane, where AKT is activated through ...
Interrupting one function of a protein that plays a key role in cell signaling could enable the development of new cancer ...
A large, multi-institution study led by a Brown University physician-scientist could have important implications for the ...
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