A phase II trial evaluating liposomal irinotecan combined with capecitabine as second-line therapy for biliary tract cancer.

Over six years, 552 patients with CHC completed sofosbuvir-based DAA therapy. Of these, 25 patients with active HCC, 18 patients with inactive HCC before treatment, and 26 patients who lacked blood ...

Spatial biology technologies are reshaping modern biomedical research by enabling the visualization of cellular organization ...

Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians ...

Alpha-fetoprotein-producing gastrointestinal malignancies represent a rare and aggressive subset of tumours chiefly arising in the stomach and, less commonly, the oesophagus or other segments of the ...

A novel 3D cell culture method has been developed that encourages liver progenitor cells to self-organize and form blood vessel networks for the first time. The development of accurate liver organoids ...

A new type of cell therapy shows promise as the first treatment for advanced liver disease, following results from a clinical trial. Patients with the condition who were treated with the cell therapy ...

Close-up of a human liver lobule highlighting GLUL (glutamine synthetase) + liver cells surrounding the central vein (grey), with intensity-based pseudocoloring of CD32b expression showing the highest ...